Drugs and the Rise of the Fentanyl Epidemic
- Marcelo Serafim
- Oct 6
- 4 min read
1. Ancient Roots of Medicine and Drugs
The use of drugs dates back thousands of years, long before modern science existed. Ancient civilizations such as the Egyptians, Greeks, and Chinese used natural substances like herbs, roots, and opium poppies to treat pain and disease. These early societies often mixed medicine with religion, believing that healing came from divine or mystical sources. While their understanding of chemistry was limited, their experiments laid the foundation for pharmacology — the science of studying drugs.

2. The Birth of Modern Pharmacology
During the 19th century, scientific methods revolutionized medicine. Chemists learned how to isolate active compounds from plants, leading to the creation of drugs like morphine, derived from opium, and aspirin, derived from willow bark. This was also when the pharmaceutical industry began to emerge. Drugs were no longer made by healers or apothecaries but by laboratories using controlled formulas and doses.
3. The Rise of Synthetic Drugs
In the early 20th century, researchers began creating synthetic drugs — chemicals made entirely in laboratories. These innovations helped treat infections and diseases that had previously been fatal. For instance, penicillin saved millions of lives during World War II. However, this same scientific progress also opened the door for addictive substances like amphetamines and barbiturates, which were often misused.
4. The Counterculture and Drug Revolution
The 1960s marked a cultural shift in the use of drugs. Psychedelics such as LSD, marijuana, and mescaline became symbols of rebellion and freedom among young people. Governments around the world responded with strict anti-drug laws. Despite this, illegal production and trafficking increased dramatically, giving rise to international drug cartels and underground markets.

5. The Prescription Drug Boom
In the 1990s, the medical field saw an explosion in the prescription of painkillers, particularly opioids like oxycodone and hydrocodone. Pharmaceutical companies marketed these drugs aggressively, claiming they were safe and effective. However, many patients developed dependence, and addiction rates soared. This era marked the beginning of the opioid crisis, which continues to affect millions worldwide.
6. The Transition to Illicit Opioids
As prescription opioids became harder to obtain due to tighter regulations, many addicted individuals turned to heroin — a cheaper and more accessible alternative. Heroin use spread rapidly, especially in economically vulnerable communities. The illegal trade of opioids became a global industry worth billions of dollars.
7. The Arrival of Fentanyl
In the 2010s, a new and more dangerous opioid entered the scene: fentanyl. Originally developed as a legitimate painkiller for cancer patients, fentanyl is 50 times stronger than heroin and 100 times more potent than morphine. Drug traffickers began mixing it into heroin, cocaine, and counterfeit pills, often without users’ knowledge. This resulted in a dramatic increase in overdoses and deaths.
8. The Epidemic’s Devastating Impact
The fentanyl epidemic has devastated communities across North America and beyond. Thousands of people die each year from overdoses involving synthetic opioids. The crisis has overwhelmed healthcare systems, strained law enforcement, and torn families apart. Governments are now investing in education, addiction treatment, and harm reduction strategies, such as providing naloxone kits to reverse overdoses.
9. Global Efforts and Future Challenges
The international community is working to control the production and distribution of synthetic opioids. However, because fentanyl can be made in small quantities using easily obtained chemicals, it remains difficult to regulate. Meanwhile, researchers are exploring new non-addictive pain treatments, and educators are emphasizing prevention through awareness programs.

10. Lessons from the Past
The history of drugs reveals a constant tension between healing and harm. Each new discovery has the potential to save lives — or destroy them if misused. The fentanyl epidemic is a tragic reminder that scientific progress must always be guided by ethics, responsibility, and compassion. Understanding how we got here is essential to preventing the next public health crisis.
📝 Comprehension Questions
What were some of the earliest natural substances used as medicines?
How did the rise of the pharmaceutical industry change the production of drugs?
What caused the increase in opioid addiction in the 1990s?
Why is fentanyl considered more dangerous than other opioids?
What are some of the strategies used to fight the fentanyl epidemic today?
📚 Vocabulary Section
Word | Meaning |
Pharmacology | The branch of medicine that studies drugs and their effects. |
Synthetic | Artificially made, not naturally occurring. |
Psychedelics | Drugs that cause hallucinations and altered perception. |
Dependence | The state of needing something regularly, especially a drug. |
Regulations | Rules made by authorities to control certain activities. |
Counterfeit | Made to imitate something genuine, usually for deception. |
Devastating | Causing great harm, damage, or emotional pain. |
Harm reduction | Policies or programs aimed at minimizing the negative effects of drug use. |
Illicit | Forbidden by law or rules. |
Ethics | Moral principles that govern behavior or actions. |
💬 Phrasal Verb: “Crack down on”
Meaning: To take strong action to stop or control something.Examples:
The government is cracking down on illegal drug trafficking.
Schools are cracking down on the use of vaping devices among students.
🇺🇸 American Idiom: “A double-edged sword”
Meaning: Something that has both positive and negative consequences.Example:
The invention of opioids was a double-edged sword — it relieved pain but also led to addiction.
🧩 English Grammar Tip: Past Perfect Tense
Use the past perfect to describe an action that happened before another action in the past.Form: had + past participleExamples:
Many people had already developed addictions before the government took action.
Scientists had discovered morphine long before synthetic drugs appeared.
Listening
🏠 Homework Proposal
Write a 250-word essay answering the question:
“Do you think the benefits of medical drug development outweigh the risks of addiction and misuse?”
Use at least three vocabulary words from the list above, one phrasal verb, and one idiom. Pay attention to verb tenses and sentence structure.



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